Neuroauditory Toxicity of Artemisinin Combination Therapies—Have Safety Concerns Been Addressed?
نویسندگان
چکیده
منابع مشابه
Neuroauditory Toxicity of Artemisinin Combination Therapies—Have Safety Concerns Been Addressed?
Although artemisinin-based combination therapies (ACTs) are widely viewed as safe drugs with a wide therapeutic dose range, concerns about neuroauditory safety of artemisinins arose during their development. A decade ago, reviews of human data suggested a potential neuro-ototoxic effect, but the validity of these findings was questioned. With 5-10 years of programmatic use, emerging artemisinin...
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ژورنال
عنوان ژورنال: The American Journal of Tropical Medicine and Hygiene
سال: 2014
ISSN: 0002-9637,1476-1645
DOI: 10.4269/ajtmh.13-0702